Anti nausea drug linked to stroke risk in study

Written by on 24 March 2022

Anti-nausea drug linked to stroke risk in study

Research has been published in The BMJ

An anti-nausea drug has been linked to an increased risk of stroke in a new study.

Research published in The BMJ found that drugs known as antidopaminergic antiemetics (ADAs), which are widely used to relieve nausea and vomiting, could lead to an increased risk, especially in the first few days of use.

Academics in France identified 2,600 patients in a French healthcare database who had a stroke between 2012 and 2016 and who had been prescribed one of three ADAs – domperidone, metopimazine, and metoclopramide.

These were compared with almost 22,000 people who had not had a stroke.

After taking account of potentially influential factors, the researchers found that new users of ADAs had a three-fold increased risk of stroke.

The analysis suggested that the risk was higher in the “first days of use”.

“Use of antidopaminergic antiemetics is associated with an increased risk of ischaemic stroke,” the authors wrote.

“The highest risk was observed for metopimazine and metoclopramide.”

Published: by Radio NewsHub

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